产品货号：
Z29265
中文名称：
WFS1抗体
英文名称：
Anti-WFS1 Antibody
产品规格：
50μl|100μl|150μl
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-WFS1 Antibody |
| 指标别名 | WFRS;WFS;WFS1;Wolfram syndrome 1 (wolframin);WOLFRAMIN |
| 克隆性 | Polyclonal |
| 检验物种 | human,monkey |
| 应用范围 | WB,IHC,ICC/IF,FCM,ELISA |
| 基因名称 | WFS1 |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | E.coli-derived human WFS1 recombinant protein (Position:A61-H313). |
| 实际分子量 | 100KD |
| 成分 | 500μg/mL antibody with PBS，0.02% NaN3,1mg BSA and 50% glycerol. |
| 纯化方式 | Immunogen affinity purified. |
| 浓度 | 500μg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 12 months from date of receipt，-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing. |
| 背景资料 | Wolframin is a protein that in humans is encoded by the WFS1 gene.This gene encodes a transmembrane protein,which is located primarily in the endoplasmic reticulum and ubiquitously expressed with highest levels in brain,pancreas,heart,and insulinoma beta-cell lines.Mutations in this gene are associated with Wolfram syndrome,also called DIDMOAD (Diabetes Insipidus,Diabetes Mellitus,Optic Atrophy,and Deafness),an autosomal recessive disorder.The disease affects the brain and central nervous system.Mutations in this gene can also cause autosomal dominant deafness 6 (DFNA6),also known as DFNA14 or DFNA38.Alternatively spliced transcript variants have been found for this gene. |
| Uniprot ID | O76024 |
| 推荐配套试剂 | Biorab recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ZN1926) for Western blot. |
| 基因名全称 | wolframin ER transmembrane glycoprotein |
| 蛋白名全称 | Wolframin |
| 推荐稀释比 | Western blot (WB) 1:500～2000 Immunohistochemistry (IHC) 1:50～400 Immunocytochemistry/Immunofluorescence (ICC/IF) 1:50～400 Flow cytometry (FCM) 1～3μg/1×106 cells Enzyme linked immunosorbent assay (ELISA) 1:100～1000 (Boiling the paraffin sections in 10mM citrate buffer,pH6.0,or PH8.0 EDTA repair liquid for 20 mins is required for the staining of formalin/paraffin sections.) Optimal working dilutions must be determined by end user. |
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